Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NME2 All Species: 54.85
Human Site: T103 Identified Species: 92.82
UniProt: P22392 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22392 NP_001018146.1 152 17298 T103 P A D S K P G T I R G D F C I
Chimpanzee Pan troglodytes XP_001147407 308 33377 T259 P A D S K P G T I R G D F C I
Rhesus Macaque Macaca mulatta XP_001096144 240 26905 T191 P A D S K P G T I R G D F C I
Dog Lupus familis XP_533973 152 17223 T103 P A D S K P G T I R G D F C I
Cat Felis silvestris
Mouse Mus musculus Q01768 152 17345 T103 P A D S K P G T I R G D F C I
Rat Rattus norvegicus P19804 152 17264 T103 P A D S K P G T I R G D F C I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515701 267 30034 T103 P A D S K P G T I R G D F C I
Chicken Gallus gallus O57535 153 17269 T104 P A D S K P G T I R G D F C I
Frog Xenopus laevis P70011 154 17484 T104 P A D S K P G T I R G D L C I
Zebra Danio Brachydanio rerio NP_571001 153 17215 T104 P A D S K P G T I R G D F C I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08879 153 17151 T104 P A D S L P G T I R G D F C I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LAH8 237 25755 T186 P Q K S E P G T I R G D L A V
Baker's Yeast Sacchar. cerevisiae P36010 153 17148 T104 P L G S A P G T I R G D F G I
Red Bread Mold Neurospora crassa Q9UUY8 152 16882 T103 P L A S A P G T I R G D F A L
Conservation
Percent
Protein Identity: 100 46.4 57 84.8 N.A. 98 98 N.A. 54.3 91.5 86.3 86.9 N.A. 77.1 N.A. N.A. N.A.
Protein Similarity: 100 47.7 60.8 92.1 N.A. 99.3 99.3 N.A. 55.8 96 94.8 92.8 N.A. 86.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 100 N.A. 93.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 100 N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 40 60.1 63.1
Protein Similarity: N.A. N.A. N.A. 51 79 79.6
P-Site Identity: N.A. N.A. N.A. 60 73.3 66.6
P-Site Similarity: N.A. N.A. N.A. 73.3 73.3 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 79 8 0 15 0 0 0 0 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 79 0 % C
% Asp: 0 0 79 0 0 0 0 0 0 0 0 100 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 86 0 0 % F
% Gly: 0 0 8 0 0 0 100 0 0 0 100 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 86 % I
% Lys: 0 0 8 0 72 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 15 0 0 8 0 0 0 0 0 0 0 15 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 100 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % R
% Ser: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _